The Wildcats (8-6, 6-0 SoCon) hit their first eight shots on their way to a 21-5 lead and shot better than 63 percent from the floor. Will Archambault added 15 points and Boris Meno led all rebounders with nine.
The Terriers (8-7, 1-4), who shot just 36 percent from the floor, were led by Shane Nichols with 14 points.
Wofford cut the lead to 28-13 with 7:54 left in the half, but Davidson quickly extended the lead to 23 and led 45-25 at the half.
Davidson led by as many as 43 at 79-36 in the second half and outrebounded Wofford 36-17.